Saturday, April 08, 2006

Active and passive smoking and development of glucose intolerance among young adults in a prospective cohort: CARDIA study -- Houston et al., 10.1136/

Active and passive smoking and development of glucose intolerance among young adults in a prospective cohort: CARDIA study -- Houston et al., 10.1136/bmj.38779.584028.55 -- BMJ: "Results Median age at baseline was 25, 55% of participants were women, and 50% were African-American. During follow-up, 16.7% of participants developed glucose intolerance. A graded association existed between smoking exposure and the development of glucose intolerance. The 15 year incidence of glucose intolerance was highest among smokers (21.8%), followed by never smokers with passive smoke exposure (17.2%), and then previous smokers (14.4%); it was lowest for never smokers with no passive smoke exposure (11.5%). Current smokers (hazard ratio 1.65, 95% confidence interval 1.27 to 2.13) and never smokers with passive smoke exposure (1.35, 1.06 to 1.71) remained at higher risk than never smokers without passive smoke exposure after adjustment for multiple baseline sociodemographic, biological, and behavioural factors, but risk in previous smokers was similar to that in never smokers without passive smoke exposure."

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